International Journal of Ophthalmology & Visual Science

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Clinical Characterization of Surgical Opportunities in Proliferative Diabetic Retinopathy - A Population-Based Study

Received: 14 October 2023    Accepted: 27 October 2023    Published: 9 November 2023
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Abstract

Background: Proliferative diabetic retinopathy is the most common complication of diabetes. Long-term high blood sugar damage to retinal blood vessels, including arteriosclerosis, tissue ischemia, hypoxia, compensatory neovascularization and other pathological changes. It is divided into non-proliferative period and proliferative period. Then the treatment is to control blood sugar and take medicine to treat it conservatively. When vision declines, eyeball changes and retinopathy reach a certain level, when surgery is particularly critical. Early surgical treatment is not enough. The late operation misses the opportunity, which affects the effect of surgical treatment and even aggravates the condition. At present, the timing of the operation is still controversial. It is necessary to study the clinical characteristic analysis of surgical opportunities for proliferative diabetic retinopathy. The research will explain the advantages and disadvantages and the research results. Research methods: Vitrectomy was performed on 66 patients (89 eyes) with PDR hospitalized from January 2020 to January 2023. During the operation, different surgical treatment methods were used according to the situation, so that the omentum was well restored. Patients were followed up after surgical treatment. This includes improvement in corrected vision after 3 months, 6 months, and 12 months, no improvement or decline in vision, and loss of eye vision. In the clinical study, the improvement of visual acuity in stage IV to V, the treatment of intraocular filling with silicone oil, etc. Statistical analysis and clinical characteristics were conducted based on the above data. Objective: To study and explore the clinical characteristics of surgical opportunities after retinopathy caused by diabetic complications. Results: Vitrectomy was performed on 66 patients (89 eyes) with PDR who were hospitalized between January 2020 and January 2023. During the operation, 15 eyes were treated with peeling membrane, 20 eyes were treated with retinal photocoagulation, 17 eyes were treated with gas-liquid exchange or heavy water injection, and 37 eyes were treated with C3F8 gas or silicone oil filling. Results After 3 months, 6 months and 12 months, 68 eyes were improved, 12 eyes were not improved or decreased, and 9 eyes were lost. Stage IV-V 65 eyes (stage V 31 eyes), stage VI 24 eyes. Postoperative visual acuity improved in 45 eyes in stage IV to V and 12 eyes in stage VI. 37 eyes filled with silicone oil. Stage IV to stage V 25 eyes, stage VI 12 eyes.

DOI 10.11648/j.ijovs.20230804.11
Published in International Journal of Ophthalmology & Visual Science (Volume 8, Issue 4, December 2023)
Page(s) 48-52
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Diabetes, Diabetes Complications, Retinopathy, Surgical Treatment, Vitrectomy, Vision Correction, Access to Surgery, Loss of Vision

References
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[3] Diabetic Retinopathy Vitrectomy Study Research Group. Earlvitrectomy for severe proliferative diabetic retinopathy ineyes with useful vision. Res of a randomized trial: Diabetic Retinopathy Vitrectomy Study Report 3 [J]. OphthalMol 2022. 95: 107.
[4] Diabetic Retinopathy Vitrectomy Study Research Group: Early vitrectomy for severe vitreous hemorrhage in diabetic retiNopathy Diabetic Retinopathy Vitrectomy Study Report [J]. Ophthalmol 2021. 108: 958.
[5] Grewing, RMester U. Early vitrectomy for progressive diabetic proliferations covering the macular [J] BrJOphthal Mol? 2022. 78: 433.
[6] Ferris F. Early photocoagulation in patients with either typeIor typeII diabetes [J]. Trans Am Ophthalmol Soc 2023 94: 505.
[7] Wu Fan, Zhu Xiaobo, He Yongning. The timing of vitrectomy in patients with proliferative diabetic retinopathy and its effect on vision improvement [J]. Journal of Baotou Medical College, 2019, 35 (09): 51-52.
[8] Li Chunyan, Zhu Antai. Choosing the timing of diabetic retinopathy complicated with vitreous volume blood surgery [J]. Journal of Xinxiang Medical College, 2021, 35 (08): 731-734.
[9] Zhang Hongying. Retrospective analysis of the prognosis of visual function of stage V and stage VI diabetic retinopathy [D]. Guangzhou University of Traditional Chinese Medicine, 2019.
[10] Zhang Qi, Feng Jie, Cheng Xukang, etc. Timing of cataract surgery for severe non-proliferative diabetic retinopathy [J]. International Journal of Ophthalmology, 2023, 13 (01): 92-93.
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[16] Long Ting, Chen Jia, Du Lei, etc. Advances in surgical treatment of proliferative diabetic retinopathy [J]. International Journal of Ophthalmology, 2017, 17 (11): 2069-2072.
[17] Liu Sanmei, Li Jie, Dong Wentao, etc. Medium- and long-term clinical observation of intravitreous injection of Compasipp and retinal photocoagulation in the treatment of proliferative diabetic retinopathy [J]. Journal of Chengdu University of Traditional Chinese Medicine, 2020, 40 (01): 63-65.
[18] Ke Yi, Zhang Yuan, Wang Xiuqin, etc. Comprehensive Study on the Efficacy of Conservative Treatment and Surgical Treatment of Glass Volume Blood [J]. Chinese practical medicine, 2020, 15 (16): 20-22.
[19] Jiang Shengqun. Effects of different timings of leizhumonumab on the effect of vitreous excision for hyperplasia of diabetic retinopathy [J]. Journal of Mudanjiang Medical College, 2019, 40 (04): 78-80. DOI: 10.13799/j.cnki.mdjyxyxb.2019.04.026.
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    Tao, W., Chao, L. (2023). Clinical Characterization of Surgical Opportunities in Proliferative Diabetic Retinopathy - A Population-Based Study. International Journal of Ophthalmology & Visual Science, 8(4), 48-52. https://doi.org/10.11648/j.ijovs.20230804.11

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    ACS Style

    Tao, W.; Chao, L. Clinical Characterization of Surgical Opportunities in Proliferative Diabetic Retinopathy - A Population-Based Study. Int. J. Ophthalmol. Vis. Sci. 2023, 8(4), 48-52. doi: 10.11648/j.ijovs.20230804.11

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    AMA Style

    Tao W, Chao L. Clinical Characterization of Surgical Opportunities in Proliferative Diabetic Retinopathy - A Population-Based Study. Int J Ophthalmol Vis Sci. 2023;8(4):48-52. doi: 10.11648/j.ijovs.20230804.11

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  • @article{10.11648/j.ijovs.20230804.11,
      author = {Wang Tao and Liu Chao},
      title = {Clinical Characterization of Surgical Opportunities in Proliferative Diabetic Retinopathy - A Population-Based Study},
      journal = {International Journal of Ophthalmology & Visual Science},
      volume = {8},
      number = {4},
      pages = {48-52},
      doi = {10.11648/j.ijovs.20230804.11},
      url = {https://doi.org/10.11648/j.ijovs.20230804.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20230804.11},
      abstract = {Background: Proliferative diabetic retinopathy is the most common complication of diabetes. Long-term high blood sugar damage to retinal blood vessels, including arteriosclerosis, tissue ischemia, hypoxia, compensatory neovascularization and other pathological changes. It is divided into non-proliferative period and proliferative period. Then the treatment is to control blood sugar and take medicine to treat it conservatively. When vision declines, eyeball changes and retinopathy reach a certain level, when surgery is particularly critical. Early surgical treatment is not enough. The late operation misses the opportunity, which affects the effect of surgical treatment and even aggravates the condition. At present, the timing of the operation is still controversial. It is necessary to study the clinical characteristic analysis of surgical opportunities for proliferative diabetic retinopathy. The research will explain the advantages and disadvantages and the research results. Research methods: Vitrectomy was performed on 66 patients (89 eyes) with PDR hospitalized from January 2020 to January 2023. During the operation, different surgical treatment methods were used according to the situation, so that the omentum was well restored. Patients were followed up after surgical treatment. This includes improvement in corrected vision after 3 months, 6 months, and 12 months, no improvement or decline in vision, and loss of eye vision. In the clinical study, the improvement of visual acuity in stage IV to V, the treatment of intraocular filling with silicone oil, etc. Statistical analysis and clinical characteristics were conducted based on the above data. Objective: To study and explore the clinical characteristics of surgical opportunities after retinopathy caused by diabetic complications. Results: Vitrectomy was performed on 66 patients (89 eyes) with PDR who were hospitalized between January 2020 and January 2023. During the operation, 15 eyes were treated with peeling membrane, 20 eyes were treated with retinal photocoagulation, 17 eyes were treated with gas-liquid exchange or heavy water injection, and 37 eyes were treated with C3F8 gas or silicone oil filling. Results After 3 months, 6 months and 12 months, 68 eyes were improved, 12 eyes were not improved or decreased, and 9 eyes were lost. Stage IV-V 65 eyes (stage V 31 eyes), stage VI 24 eyes. Postoperative visual acuity improved in 45 eyes in stage IV to V and 12 eyes in stage VI. 37 eyes filled with silicone oil. Stage IV to stage V 25 eyes, stage VI 12 eyes.
    },
     year = {2023}
    }
    

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  • TY  - JOUR
    T1  - Clinical Characterization of Surgical Opportunities in Proliferative Diabetic Retinopathy - A Population-Based Study
    AU  - Wang Tao
    AU  - Liu Chao
    Y1  - 2023/11/09
    PY  - 2023
    N1  - https://doi.org/10.11648/j.ijovs.20230804.11
    DO  - 10.11648/j.ijovs.20230804.11
    T2  - International Journal of Ophthalmology & Visual Science
    JF  - International Journal of Ophthalmology & Visual Science
    JO  - International Journal of Ophthalmology & Visual Science
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    EP  - 52
    PB  - Science Publishing Group
    SN  - 2637-3858
    UR  - https://doi.org/10.11648/j.ijovs.20230804.11
    AB  - Background: Proliferative diabetic retinopathy is the most common complication of diabetes. Long-term high blood sugar damage to retinal blood vessels, including arteriosclerosis, tissue ischemia, hypoxia, compensatory neovascularization and other pathological changes. It is divided into non-proliferative period and proliferative period. Then the treatment is to control blood sugar and take medicine to treat it conservatively. When vision declines, eyeball changes and retinopathy reach a certain level, when surgery is particularly critical. Early surgical treatment is not enough. The late operation misses the opportunity, which affects the effect of surgical treatment and even aggravates the condition. At present, the timing of the operation is still controversial. It is necessary to study the clinical characteristic analysis of surgical opportunities for proliferative diabetic retinopathy. The research will explain the advantages and disadvantages and the research results. Research methods: Vitrectomy was performed on 66 patients (89 eyes) with PDR hospitalized from January 2020 to January 2023. During the operation, different surgical treatment methods were used according to the situation, so that the omentum was well restored. Patients were followed up after surgical treatment. This includes improvement in corrected vision after 3 months, 6 months, and 12 months, no improvement or decline in vision, and loss of eye vision. In the clinical study, the improvement of visual acuity in stage IV to V, the treatment of intraocular filling with silicone oil, etc. Statistical analysis and clinical characteristics were conducted based on the above data. Objective: To study and explore the clinical characteristics of surgical opportunities after retinopathy caused by diabetic complications. Results: Vitrectomy was performed on 66 patients (89 eyes) with PDR who were hospitalized between January 2020 and January 2023. During the operation, 15 eyes were treated with peeling membrane, 20 eyes were treated with retinal photocoagulation, 17 eyes were treated with gas-liquid exchange or heavy water injection, and 37 eyes were treated with C3F8 gas or silicone oil filling. Results After 3 months, 6 months and 12 months, 68 eyes were improved, 12 eyes were not improved or decreased, and 9 eyes were lost. Stage IV-V 65 eyes (stage V 31 eyes), stage VI 24 eyes. Postoperative visual acuity improved in 45 eyes in stage IV to V and 12 eyes in stage VI. 37 eyes filled with silicone oil. Stage IV to stage V 25 eyes, stage VI 12 eyes.
    
    VL  - 8
    IS  - 4
    ER  - 

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Author Information
  • Department of Ophthalmology, Ding Zhou Tian Shun Eye Hospital, Baoding, China

  • Department of Surgery, Clinical Medicine, Universitas Prima Indonesia, Medan, Indonesia

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