Volume 3, Issue 2, June 2018, Page: 21-26
Research Progress on Corneal Collagen Cross-Linking for Corneal Ulcerative Keratitis
Feng Dan, Department of Medical College, Hunan normal University, Changsha, China
He Shuxi, Center for Ophthalmic Optics, Hunan Provincial People's Hospital, Changsha, China
Received: May 29, 2018;       Accepted: Jul. 4, 2018;       Published: Jul. 27, 2018
DOI: 10.11648/j.ijovs.20180302.12      View  458      Downloads  31
Abstract
Corneal collagen cross-linking (CXL) is a photochem therapy for keratoconus, keratectasias and infectious keratitis. Corneal collagen fiber infiltrated with riboflavin, a photosensitizer which generates reactive oxygen species when activated by UVA, was induced to form the cross-links in corneal stroma. The purpose of this paper is to review the basic principle, therapeutic potential of corneal ulcerative disease, existing evidences from laboratory and clinical studies, and relevant limitations, then put forward the advantages of CXL in the treatment of corneal ulcerative disease, and thus provide more possibilities for the treatment of the disease.
Keywords
Corneal Collagen Cross-Linking (CXL), Ultraviolet Light A (UVA), Riboflavin, Ulcerative Disease
To cite this article
Feng Dan, He Shuxi, Research Progress on Corneal Collagen Cross-Linking for Corneal Ulcerative Keratitis, International Journal of Ophthalmology & Visual Science. Vol. 3, No. 2, 2018, pp. 21-26. doi: 10.11648/j.ijovs.20180302.12
Copyright
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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