Volume 3, Issue 2, June 2018, Page: 32-38
A Correlative Study of Intra Ocular Pressure, Mean Arterial Pressure and CSF Pressure in Non Neurological Patients
Pragati Garg, Department of Ophthalmology, Era’s Lucknow Medical College and Hospital, Lucknow, India
Smriti Diwedi, Department of Ophthalmology, Era’s Lucknow Medical College and Hospital, Lucknow, India
Ritika Mullick, Department of Ophthalmology, Era’s Lucknow Medical College and Hospital, Lucknow, India
Received: Aug. 24, 2018;       Accepted: Sep. 11, 2018;       Published: Oct. 15, 2018
DOI: 10.11648/j.ijovs.20180302.14      View  176      Downloads  9
Abstract
Introduction: Blood pressure is one of the most important and most widely studied factors affecting the IOP. Another important factor that plays an important role in pathogenesis of glaucoma is cerebrospinal fluid pressure. The present study was planned to study the relationship between intraocular pressure, mean arterial pressure and estimated Cerebrospinal fluid pressure in non-neurological patients. Material and Method: The present study was conducted in the Department of Ophthalmology. The study was carried out as a case-control study for 18 months. The patients above 40 years of age irrespective of sex were included in the study after their informed consent. Total of 250 patients were taken out of which 150 were cases with signs of glaucoma and 100 were controls with no signs of glaucoma. Result: 250 subjects enrolled in the study, a total of 150 (60%) were clinically established cases of glaucoma (with IOP >22mmHg) and comprised the case group of study whereas remaining 100 were apparently healthy subjects with no signs and symptoms of glaucoma and had IOP <22 mmHg and comprised the control group of the study. Mean ICP values of subjects with IOP 31-40 mm Hg were significantly higher as compared to those with IOP 23-30 mm Hg and ≤22 mmHg respectively (p=0.002). Mean Arterial Pressure (MAP) showed a significant near mild positive correlation with IOP (r=0.288; p<0.001) and a moderate positive correlation with ICP (r=0.520; p<0.001). However, the correlation between IOP and ICP was weak positive but significant (p=0.010). The relationship between gender and mean MAP and IOP and ICP was evaluated, and the values of all of them were higher in males as compared to females, but the difference was significant only for mean IOP and ICP (p=0.180 and p<0.001 respectively). Conclusion: The findings in present study thus indicate that the relationship between IOP, ICP and MAP is governed by a multitude of factors (in present study these covariates were age, gender and BMI). The present study was unique in the sense that it was probably the first Indian study exploring relationship between IOP, MAP and ICP, and that too in healthy individuals.
Keywords
Intra Ocular Pressure, Mean Arterial Pressure, Cerebrospinal Fluid Pressure, Non-Neurological Patients
To cite this article
Pragati Garg, Smriti Diwedi, Ritika Mullick, A Correlative Study of Intra Ocular Pressure, Mean Arterial Pressure and CSF Pressure in Non Neurological Patients, International Journal of Ophthalmology & Visual Science. Vol. 3, No. 2, 2018, pp. 32-38. doi: 10.11648/j.ijovs.20180302.14
Copyright
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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